|
|
docosahexaenoic_acid + CoA + ATP <=> docosahexaenoyl-CoA + diphosphate + AMP
|
6.2.1.15
arachidonate---CoA ligase
6.2.1.3
long-chain-fatty-acid---CoA ligase
|
–
–
|
|
| |
BRENDA:
BS290
MetaCyc:
RXN-21762
|
|
|
|
docosahexaenoyl-CoA + H2O <=> docosahexaenoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
3.1.2.20
acyl-CoA hydrolase
|
–
–
|
K
|
| |
BRENDA:
BS360760
KEGG:
R08180
MetaCyc:
RXN-16063
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> 22-hydroxydocosahexaenoic_acid + flavin + H2O
|
1.14.14.1
unspecific monooxygenase
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
–
|
|
| |
BRENDA:
BR51076
KEGG:
R10795
|
|
|
|
docosahexaenoic_acid + reduced_[NADPH-hemoprotein_reductase] + O2 <=> 22-hydroxydocosahexaenoic_acid + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
| |
MetaCyc:
RXN-15675
|
|
|
|
acetyl-CoA + malonyl-CoA + NADPH + H+ <=> docosahexaenoic_acid + CO2 + CoA + H2O + NADP+
|
2.3.1
|
–
|
M
|
| |
MetaCyc:
RXN-16017
|
|
|
|
[glycerolipid]-(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + H2O <=> docosahexaenoic_acid + glycerolipid + H+
|
3.1.1.4
phospholipase A2
|
–
|
M
|
| |
MetaCyc:
RXN-16138
|
|
|
|
docosahexaenoic_acid + O2 + reduced_acceptor <=> (17R)-hydroxydocosahexaenoate + H2O + acceptor
|
1.13.11
|
–
|
M
|
| |
MetaCyc:
RXN66-498
|
|
|
|
docosahexaenoic_acid + O2 <=> 17S-hydroperoxydocosahexaenoate
|
1.13.11
|
–
|
M
|
| |
MetaCyc:
RXN66-510
|
|
|
|
docosahexaenoic_acid + reduced_ferredoxin_[iron-sulfur]_cluster + O2 + H+ <=> docosa-4,7,10,13,16,19-hexaenoic_acid + oxidized_ferredoxin + H2O
|
1.14.19.43
palmitoyl-[glycerolipid] 3-(E)-desaturase
|
–
|
|
| |
BRENDA:
BS433226
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,10Z,13Z,16Z)-19,20-epoxydocosa-4,7,10,13,16-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
| |
BRENDA:
BR51211
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,10Z,16Z,19Z)-13,14-epoxydocosa-4,7,10,16,19-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
| |
BRENDA:
BR51212
|
|
|
|
docosahexaenoic_acid + reduced_flavodoxin + O2 <=> (4Z,7Z,13Z,16Z,19Z)-10,11-epoxydocosa-4,7,13,16,19-pentaenoate + flavin + H2O
|
1.14.14.B9
|
–
|
|
| |
BRENDA:
BR51213
|
|
|
|
phosphatidylcholine + H2O <=> 2-acylglycerophosphocholine + eicosapentaenoic_acid + docosapentaenoic_acid + docosahexaenoic_acid
|
3.1.1.32
phospholipase A1
|
–
|
|
| |
BRENDA:
BS390285
|
|
|
|
docosahexaenoic_acid <=> (4Z,7Z,9E,11E,16Z,19Z)-docosa-4,7,9,11,16,19-hexaenoate
|
5.3.3.13
polyenoic fatty acid isomerase
|
–
|
|
| |
BRENDA:
BS371283
|
|
|
|
sphingosine + docosahexaenoic_acid <=> N-((4Z,7Z,10Z,13Z,16Z,19Z)-docosahexa-4,7,10,13,16,19-enoyl)-D-erythro-sphingosine + H2O
|
3.5.1.23
ceramidase
|
–
|
|
| |
BRENDA:
BS381730
|
|
|
|
docosahexaenoic_acid + NADPH + H+ + O2 <=> 22-hydroxydocosahexaenoic_acid + NADP+ + H2O
|
1.14.14.79
docosahexaenoic acid omega-hydroxylase
|
–
|
|
| |
BRENDA:
BS427435
|
|
|
|
ATP + docosahexaenoic_acid + CoA <=> ATP + diphosphate + docosahexaenoyl-CoA
|
6.2.1.15
arachidonate---CoA ligase
|
–
|
|
| |
BRENDA:
BS180
|
|
|
|
docosahexaenoic_acid + O2 <=> 14-hydroxy-4,7,10,12,16,19-docosahexaenoic_acid
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
| |
BRENDA:
BS260736
|
|
|
|
docosahexaenoic_acid + O2 <=> 14-hydroxy-4,7,10,13,16,19-docosahexaenoic_acid
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
| |
BRENDA:
BS260732
|
|
|
|
1,2-didocosahexaenoyl-phosphatidylcholine + H2O <=> 2-docosahexaenoyl-lysophosphatidylcholine + docosahexaenoic_acid
|
3.1.1.32
phospholipase A1
|
–
|
|
| |
BRENDA:
BS364120
|
|
|
|
docosahexaenoic_acid + 2 ferricytochrome_b5 + O2 + 2 H+ <=> docosahexaenoic_acid + 2 ferricytochrome_b5 + 2 H2O
|
1.14.19.31
acyl-lipid (7-3)-desaturase
|
–
|
|
| |
BRENDA:
BS433225
|
|
